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Anna Krasnodembskaya

Researcher at Queen's University Belfast

Publications -  57
Citations -  4626

Anna Krasnodembskaya is an academic researcher from Queen's University Belfast. The author has contributed to research in topics: Mesenchymal stem cell & ARDS. The author has an hindex of 16, co-authored 49 publications receiving 2919 citations. Previous affiliations of Anna Krasnodembskaya include University of California & University of California, San Francisco.

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Antibacterial Effect of Human Mesenchymal Stem Cells Is Mediated in Part from Secretion of the Antimicrobial Peptide LL‐37

TL;DR: Human bone marrow‐derived MSCs possess direct antimicrobial activity, which is mediated in part by the secretion of human cathelicidin hCAP‐18/ LL‐37, analysis of expression of major antimicrobial peptides indicated.
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Mesenchymal Stromal Cells Modulate Macrophages in Clinically Relevant Lung Injury Models by Extracellular Vesicle Mitochondrial Transfer

TL;DR: In the ARDS environment, MSCs promote an antiinflammatory and highly phagocytic macrophage phenotype through EV‐mediated mitochondrial transfer.
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Concise Review: Mesenchymal Stem Cells for Acute Lung Injury: Role of Paracrine Soluble Factors†‡§

TL;DR: This review will focus on recent studies, which support the potential therapeutic use of MSCs in ALI/ARDS, with an emphasis on the role of paracrine soluble factors.
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Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS.

TL;DR: It is demonstrated for the first time that mitochondrial transfer from MSC to innate immune cells leads to enhancement in phagocytic activity and reveals an important novel mechanism for the antimicrobial effect of MSC in ARDS.