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Sung Hee Baek

Researcher at Seoul National University

Publications -  122
Citations -  15508

Sung Hee Baek is an academic researcher from Seoul National University. The author has contributed to research in topics: Ubiquitin & Ubiquitin ligase. The author has an hindex of 46, co-authored 113 publications receiving 13362 citations. Previous affiliations of Sung Hee Baek include UPRRP College of Natural Sciences & Howard Hughes Medical Institute.

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MicroRNA genes are transcribed by RNA polymerase II.

TL;DR: The first direct evidence that miRNA genes are transcribed by RNA polymerase II (pol II) is presented and the detailed structure of a miRNA gene is described, for the first time, by determining the promoter and the terminator of mir‐23a∼27a‐24‐2.
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Molecular determinants of resistance to antiandrogen therapy

TL;DR: Using microarray-based profiling of isogenic prostate cancer xenograft models, it is found that a modest increase in androgen receptor mRNA was the only change consistently associated with the development of resistance to antiandrogen therapy.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein

TL;DR: It is demonstrated that interleukin-1β causes nuclear export of a specific N-CoR corepressor complex, resulting in derepression of a Specific subset of NF-κB-regulated genes, exemplified by the tetraspanin KAI1 that regulates membrane receptor function.
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Identification of a Wnt/Dvl/β-Catenin → Pitx2 Pathway Mediating Cell-Type-Specific Proliferation during Development

TL;DR: The bicoid-related transcription factor Pitx2 is rapidly induced by the Wnt/Dvl/beta-catenin pathway and is required for effective cell-type-specific proliferation by directly activating specific growth-regulating genes.