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Jiangang Shen

Researcher at University of Hong Kong

Publications -  179
Citations -  8185

Jiangang Shen is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Neuroprotection & Peroxynitrite. The author has an hindex of 45, co-authored 167 publications receiving 5777 citations. Previous affiliations of Jiangang Shen include Guangzhou University & Academia Sinica.

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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A highly selective fluorescent probe for the detection and imaging of peroxynitrite in living cells

Dan Yang, +4 more
- 14 Apr 2006 - 
TL;DR: A new fluorescent probe HKGreen-1 is successfully developed, which is highly selective for the detection of peroxynitrite in living cells, which was found a specific reaction between ketone 1 and peroxyne 1 (ONOO-), rather than other reactive oxygen species and reactive nitrogen species generated in the biological system.
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Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes

Baoying Chen, +9 more
- 10 Mar 2006 - 
TL;DR: Data suggest that hypoxia and ROS decrease adiponectin production and augment PAI-1 expression in adipocytes via distinct signaling pathways, which may contribute to hypoadiponectinemia and elevated PAI -1 levels in obesity, type 2 diabetes, and cardiovascular diseases.
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Molecular Imaging of Peroxynitrite with HKGreen-4 in Live Cells and Tissues

Tao Peng, +9 more
- 07 Aug 2014 - 
TL;DR: It is demonstrated that HKGreen-4 can be efficiently employed to visualize endogenous peroxynitrite generated in Escherichia coli-challenged macrophages and in live tissues from a mouse model of atherosclerosis.
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Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo.

Jun Jacob Hu, +10 more
- 19 May 2015 - 
TL;DR: Three new O2(•-) fluorescent probes are synthesized which exhibit excellent selectivity and sensitivity over a broad range of pH, strong oxidants, and abundant reductants found in cells, which open up exciting opportunities for unmasking the roles of O2 (•-) in health and disease.