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Michael Sendtner

Researcher at University of Würzburg

Publications -  286
Citations -  34780

Michael Sendtner is an academic researcher from University of Würzburg. The author has contributed to research in topics: Ciliary neurotrophic factor & Neurotrophic factors. The author has an hindex of 88, co-authored 269 publications receiving 31409 citations. Previous affiliations of Michael Sendtner include Hoffmann-La Roche & Regeneron.

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Journal ArticleDOI

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

Alan E. Renton, +85 more
- 20 Oct 2011 - 
TL;DR: The chromosome 9p21 amyotrophic lateral sclerosis-frontotemporal dementia (ALS-FTD) locus contains one of the last major unidentified autosomal-dominant genes underlying these common neurodegenerative diseases, and a large hexanucleotide repeat expansion in the first intron of C9ORF72 is shown.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
PatentDOI

Ciliary neurotrophic factor

Piotr Masiakowski, +13 more
- 14 Sep 1990 - 
TL;DR: In this article, the authors proposed a method for cloning and expression of ciliary neurotrophic factor (CNTF) and provided a means for producing human CNTF utilizing human CCL-encoding nucleic acid sequences.
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Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

Elisa Majounie, +71 more
- 01 Apr 2012 - 
TL;DR: A common Mendelian genetic lesion in C9orf72 is implicated in many cases of sporadic and familial ALS and FTD, suggesting a one-off expansion occurring about 1500 years ago.
Journal ArticleDOI

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy

Michael Sendtner, +2 more
- 31 May 1990 - 
TL;DR: To determine whether the vulnerability of motor neurons to axotomy in the early postnatal phase is due to insufficient availability of ciliary neurotrophic factor, transected the axons of newborn rat motor neurons and demonstrated that local application of CNTF prevents the degeneration of the corresponding cell bodies.