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Barbara Guerra

Researcher at University of Southern Denmark

Publications -  79
Citations -  8823

Barbara Guerra is an academic researcher from University of Southern Denmark. The author has contributed to research in topics: Casein kinase 2 & MAP2K7. The author has an hindex of 30, co-authored 77 publications receiving 8135 citations. Previous affiliations of Barbara Guerra include University of Copenhagen & University of Padua.

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Journal ArticleDOI

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Daniel J. Klionsky, +2522 more
- 01 Jan 2016 - 
TL;DR: Author(s): Klionsky, DJ; Abdelmohsen, K; Abe, A; Abedin, MJ; Abeliovich, H; A Frozena, AA; Adachi, H, Adeli, K, Adhihetty, PJ; Adler, SG; Agam, G; Agarwal, R; Aghi, MK; Agnello, M; Agostinis, P; Aguilar, PV; Aguirre-Ghis
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Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage.

TL;DR: It is shown that CK2 co-localizes with phosphorylated histone H2AX to sites of DNA damage and while CK2 gene knockdown is associated with delayed DNA damage repair, its overexpression accelerates this process.
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The antipsychotic drug chlorpromazine enhances the cytotoxic effect of tamoxifen in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells.

TL;DR: It is found that chlorpromazine worked synergistically together with tamoxifen with respect to reduction of cell growth and metabolic activity, both in the antiestrogen-sensitive breast cancer cell line, MCF-7, and in a tamoxIFen-resistant cell lineadays, established from the MCf-7 cells.
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Protein Kinase CK2 subunits are positive regulators of AKT kinase

TL;DR: The fact that the interaction between CK2 subunits and AKT enhances AKT kinase activity identifies a novel molecular mechanism that leads to modulation of AKT activation raising the possibility that CK2 andAKT might be implicated in common pathways that control cell proliferation and survival.
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NFκB signaling is important for growth of antiestrogen resistant breast cancer cells

TL;DR: Evidence is provided that NFκB signaling is enhanced in antiestrogens resistant breast cancer cells and plays an important role for antiestrogen resistant cell growth and for sensitivity to tamoxifen treatment in resistant cells.