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Subbiah Pugazhenthi

Researcher at Veterans Health Administration

Publications -  81
Citations -  9552

Subbiah Pugazhenthi is an academic researcher from Veterans Health Administration. The author has contributed to research in topics: CREB & Insulin. The author has an hindex of 34, co-authored 79 publications receiving 8659 citations. Previous affiliations of Subbiah Pugazhenthi include Anschutz Medical Campus & United States Department of Veterans Affairs.

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SP600125, an inhibitor of c-jun N-terminal kinase, activates CREB by a p38 MAPK-mediated pathway.

TL;DR: An additional novel anti-apoptotic action of this inhibitor is demonstrated in MIN6 cells, a mouse beta cell line, suggesting that SP600125 could be used as a small molecular weight activator of CREB.
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Dramatic Co-Activation of WWOX/WOX1 with CREB and NF-κB in Delayed Loss of Small Dorsal Root Ganglion Neurons upon Sciatic Nerve Transection in Rats

TL;DR: WOX1 is the potential target for drug intervention in mitigating symptoms associated with neuronal injury and rapid activation of JNK1 and WOX1 during the acute phase of injury is critical in determining neuronal survival or death, as both proteins functionally antagonize.
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Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Daniel J. Klionsky, +2522 more
- 01 Jan 2016 - 
TL;DR: Author(s): Klionsky, DJ; Abdelmohsen, K; Abe, A; Abedin, MJ; Abeliovich, H; A Frozena, AA; Adachi, H, Adeli, K, Adhihetty, PJ; Adler, SG; Agam, G; Agarwal, R; Aghi, MK; Agnello, M; Agostinis, P; Aguilar, PV; Aguirre-Ghis
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Varicella-Zoster Virus Infection of Differentiated Human Neural Stem Cells

TL;DR: An in vitro model of infected differentiated human neural stem cells (NSCs) providing a unique in vitro system to study the VZV-neuronal relationship and induced apoptosis in fibroblasts.
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Long-term effects of vanadate treatment on glycogen metabolizing and lipogenic enzymes of liver in genetically diabetic (db/db) mice.

TL;DR: This investigation indicates that vanadate can normalize many of the metabolic abnormalities seen in the liver of genetically diabetic db/db mice, a model for non-insulin-dependent diabetes mellitus (NIDDM), which suggests a partial reversal of insulin resistance.