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Lin Zhang

Researcher at University of Pennsylvania

Publications -  135
Citations -  26635

Lin Zhang is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Cancer & microRNA. The author has an hindex of 56, co-authored 121 publications receiving 23571 citations. Previous affiliations of Lin Zhang include University of Tennessee Health Science Center & University of Pittsburgh.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival.

Tyler J. Curiel, +20 more
- 22 Aug 2004 - 
TL;DR: It is shown, in detailed studies of CD4+CD25+FOXP3+ Treg cells in 104 individuals affected with ovarian carcinoma, that human tumor T Reg cells suppress tumor-specific T cell immunity and contribute to growth of human tumors in vivo.
Journal ArticleDOI

Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer.

Lin Zhang, +11 more
- 16 Jan 2003 - 
TL;DR: The presence of intratumoral T cells correlates with improved clinical outcome in advanced ovarian carcinoma and was associated with increased expression of interferon-gamma, interleukin-2, and lymphocyte-attracting chemokines within the tumor.
Journal ArticleDOI

microRNAs exhibit high frequency genomic alterations in human cancer

Lin Zhang, +17 more
- 13 Jun 2006 - 
TL;DR: Findings support the notion that copy number alterations of miRNAs and their regulatory genes are highly prevalent in cancer and may account partly for the frequent miRNA gene deregulation reported in several tumor types.
Journal ArticleDOI

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T reg cells

Andrea Facciabene, +10 more
- 14 Jul 2011 - 
TL;DR: It is shown that tumour hypoxia promotes the recruitment of regulatory T (Treg) cells through induction of expression of the chemokine CC-chemokine ligand 28 (CCL28), which, in turn, promotes tumour tolerance and angiogenesis.