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Matthew J. Justice

Researcher at Indiana University

Publications -  6
Citations -  5531

Matthew J. Justice is an academic researcher from Indiana University. The author has contributed to research in topics: Autophagy & Ceramide. The author has an hindex of 5, co-authored 6 publications receiving 5060 citations. Previous affiliations of Matthew J. Justice include Indiana University – Purdue University Indianapolis & University of Colorado Denver.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

17β-Estradiol Attenuates Hypoxic Pulmonary Hypertension via Estrogen Receptor–mediated Effects

Tim Lahm, +13 more
- 01 May 2012 - 
TL;DR: E2 attenuates hemodynamic and remodeling parameters in HPH in an ER-dependent manner, through direct antiproliferative mechanisms on vascular cells, which may provide novel nonhormonal therapeutic targets for HPH.
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Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: role of oxidative stress and ceramides

Kelly S. Schweitzer, +10 more
- 01 Dec 2011 - 
TL;DR: In this article, the authors investigated the occurrence and mechanisms by which soluble components of mainstream CS disrupt the lung endothelial cell barrier function using cultured primary rat microvascular cell monolayers.
Journal ArticleDOI

Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure

Kenji Mizumura, +10 more
- 01 Dec 2017 - 
TL;DR: DHCs, in particular, C24‐DHC, are implicate as protective against CS toxicity by enhancing autophagy, whereas C16‐Cer accumulation contributes to mitochondrial damage and PINKl‐mediated necroptosis, which may be amplified by the inhibition of C24-DHC‐producing CerS2.
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Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure.

Karina A. Serban, +13 more
- 27 Apr 2017 - 
TL;DR: A1AT significantly improved AM global engulfment, including phagocytosis, even when cells were simultaneously challenged with apoptotic and Fc-coated (bacteria-like) targets, and may render A1AT as a potential therapy for COPD exacerbations.