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Carolyn B. Coyne

Researcher at University of Pittsburgh

Publications -  120
Citations -  13342

Carolyn B. Coyne is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Viral replication & Trophoblast. The author has an hindex of 45, co-authored 105 publications receiving 11154 citations. Previous affiliations of Carolyn B. Coyne include University of Alabama at Birmingham & Boston Children's Hospital.

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Journal ArticleDOI

Retinoic Acid-induced Gene-1 (RIG-I) Associates with the Actin Cytoskeleton via Caspase Activation and Recruitment Domain-dependent Interactions

Amitava Mukherjee, +7 more
- 06 Mar 2009 - 
TL;DR: It is reported that retinoic acid-induced gene-I (RIG-I), an important viral RNA recognition molecule, is associated with the actin cytoskeleton and localizes predominantly to actin-enriched membrane ruffles in non-polarized epithelial cells.
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Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Daniel J. Klionsky, +2522 more
- 01 Jan 2016 - 
TL;DR: Author(s): Klionsky, DJ; Abdelmohsen, K; Abe, A; Abedin, MJ; Abeliovich, H; A Frozena, AA; Adachi, H, Adeli, K, Adhihetty, PJ; Adler, SG; Agam, G; Agarwal, R; Aghi, MK; Agnello, M; Agostinis, P; Aguilar, PV; Aguirre-Ghis
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The role of trophoblastic microRNAs in placental viral infection.

Jean-Francois Mouillet, +4 more
- 10 Jul 2014 - 
TL;DR: Interestingly, a fraction of these placenta-enriched miRNAs are released to the extracellular environment through exosomes that were recently found to induce an antiviral immunity.
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RIP3 Regulates Autophagy and Promotes Coxsackievirus B3 Infection of Intestinal Epithelial Cells

Katharine G. Harris, +8 more
- 12 Aug 2015 - 
TL;DR: Results show that temporal targeting of RIP3 allows CVB to benefit from its roles in regulating autophagy while inhibiting the induction of necroptotic cell death.
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Autophagy as a mechanism of antiviral defense at the maternal-fetal interface.

Elizabeth Delorme-Axford, +3 more
- 08 Oct 2013 - 
TL;DR: These findings establish an exciting and novel mechanism by which placental trophoblasts exploit exosome-dependent transfer of placental-specific miRNAs to influence autophagic induction and antiviral immunity at the maternal–fetal interface.