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Javier Díaz-Nido

Researcher at Spanish National Research Council

Publications -  96
Citations -  15638

Javier Díaz-Nido is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Phosphorylation & Casein kinase 2. The author has an hindex of 46, co-authored 93 publications receiving 14010 citations. Previous affiliations of Javier Díaz-Nido include Autonomous University of Madrid & Centra.

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A clonal cell line from immortalized olfactory ensheathing glia promotes functional recovery in the injured spinal cord.

TL;DR: Examination of the capacity of TEG3 to promote axonal repair in an animal model of spinal cord injury, dorsal column crush indicates that certain immortalized cell lines derived from a single cell can maintain the regenerative properties of primary OEG.
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Silencing of frataxin gene expression triggers p53-dependent apoptosis in human neuron-like cells

TL;DR: The results suggest that frataxin gene silencing in human neuron-like cells may constitute a useful cell model to characterize the molecular changes triggered by fratxin deficiency in neurons, as well as to search for therapies that may protect against neurodegeneration.
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Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Daniel J. Klionsky, +2522 more
- 01 Jan 2016 - 
TL;DR: Author(s): Klionsky, DJ; Abdelmohsen, K; Abe, A; Abedin, MJ; Abeliovich, H; A Frozena, AA; Adachi, H, Adeli, K, Adhihetty, PJ; Adler, SG; Agam, G; Agarwal, R; Aghi, MK; Agnello, M; Agostinis, P; Aguilar, PV; Aguirre-Ghis
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Glycogen Synthase Kinase-3 Modulates Neurite Outgrowth in Cultured Neurons: Possible Implications for Neurite Pathology in Alzheimer's Disease

TL;DR: It is described that a low concentration of lithium, which can partially inhibit endogenous GSK-3, favored the extension of neurites from developing neurons, whereas a high concentration of Lithium impaired neurite growth, consistent with a role for G SKS-3 in the regulation of cytoskeletal dynamics during neuritegrowth.
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Infectious delivery and expression of a 135 kb human FRDA genomic DNA locus complements Friedreich's ataxia deficiency in human cells.

TL;DR: The construction and delivery of high capacity herpes simplex virus type 1 (HSV-1) amplicon vectors expressing the entire FRDA genomic locus, driven by the endogenous FRDA promoter and including all introns and flanking regulatory sequences within a 135 kb genomic DNA insert are described.