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Emad S. Alnemri

Researcher at Thomas Jefferson University

Publications -  228
Citations -  75133

Emad S. Alnemri is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Apoptosis & Caspase. The author has an hindex of 106, co-authored 223 publications receiving 67441 citations. Previous affiliations of Emad S. Alnemri include QIMR Berghofer Medical Research Institute & Laval University.

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Journal ArticleDOI

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, +6 more
- 14 Nov 1997 - 
TL;DR: Mutation of the active site of caspase-9 attenuated the activation of cazase-3 and cellular apoptotic response in vivo, indicating that casp enzyme-9 is the most upstream member of the apoptotic protease cascade that is triggered by cytochrome c and dATP.
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Lorenzo Galluzzi, +186 more
- 23 Jan 2018 - 
TL;DR: The Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives.
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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death

Guido Kroemer, +29 more
- 25 Oct 2005 - 
TL;DR: This study details the 2009 recommendations of the NCCD on the use of cell death-related terminology including ‘entosis’, ‘mitotic catastrophe”,’ ‘necrosis‚ ‘necroptosis‚’ and ‘pyroptotic’.
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Human ICE/CED-3 Protease Nomenclature

Emad S. Alnemri, +6 more
- 18 Oct 1996 - 
TL;DR: A committee of several scientists who have been involved in the identification and characterization of these enzymes have formed a committee, with the objective of proposing a nomenclature for the human members of this protease family that is sensible and easy to use.