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Jens Schmidt

Researcher at University of Göttingen

Publications -  77
Citations -  7576

Jens Schmidt is an academic researcher from University of Göttingen. The author has contributed to research in topics: Inclusion body myositis & Skeletal muscle. The author has an hindex of 25, co-authored 73 publications receiving 6706 citations. Previous affiliations of Jens Schmidt include National Institutes of Health & Foundation University, Islamabad.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Effect of Alemtuzumab (CAMPATH 1-H) in patients with inclusion-body myositis

Marinos C. Dalakas, +11 more
- 01 Jun 2009 - 
TL;DR: It is concluded that in sIBM one series of Alemtuzumab infusions can slow down disease progression up to 6 months, improve the strength of some patients, and reduce endomysial inflammation and stressor molecules.
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Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis.

Jens Schmidt, +5 more
- 01 Aug 2003 - 
TL;DR: PL is a highly effective drug in treatment of EAE, and is superior to a 5-fold higher dose of free MP, possibly by means of drug targeting, and may have implications for future therapy of autoimmune disorders such as multiple sclerosis.
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Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle.

Jens Schmidt, +5 more
- 01 May 2008 - 
TL;DR: The data suggest that, in sIBM muscle, production of high amounts of pro-inflammatory mediators specifically induces β-amyloid-associated degeneration, and may help to design targeted treatment strategies for chronic inflammatory disorders of the skeletal muscle.
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The EuroMyositis registry: an international collaborative tool to facilitate myositis research

James B. Lilleker, +31 more
- 01 Jan 2018 - 
TL;DR: The findings emphasise that IIM is a multisystem inflammatory disease and will help inform prognosis and clinical management of patients, and demonstrate the importance of extramuscular involvement in patients with IIM, its association with smoking and its influence on disease severity.