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Sug Hyung Lee

Researcher at Catholic University of Korea

Publications -  463
Citations -  23933

Sug Hyung Lee is an academic researcher from Catholic University of Korea. The author has contributed to research in topics: Frameshift mutation & Germline mutation. The author has an hindex of 64, co-authored 454 publications receiving 21552 citations. Previous affiliations of Sug Hyung Lee include Chung-Ang University & The Catholic University of America.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas

TL;DR: In this paper, the authors performed mutational analysis of the PIK3CA gene by polymerase chain reaction-single-strand conformation polymorphism assay in 668 cases of common human cancers, including hepatocellular carcinomas, acute leukemias, gastric carcinoma, breast carcinomas and non-small-cell lung cancers.
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Increased expression of histone deacetylase 2 is found in human gastric cancer

TL;DR: Analysis of the expression of HDAC2 in 71 gastric adenocarcinomas by immunohistochemistry suggests thatHDAC2 may play an important role in the aggressiveness of gastric cancer.
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Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin.

TL;DR: The study demonstrated here that NRF2 mutation occurs not only in lung and head/neck cancers, but also in oesophageal and skin cancers, and suggests that the NRf2 mutation plays a role in the development of SCC and is a feature of S CC.