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Xu Liu

Researcher at University of Michigan

Publications -  35
Citations -  7538

Xu Liu is an academic researcher from University of Michigan. The author has contributed to research in topics: Autophagy & Autophagosome. The author has an hindex of 16, co-authored 30 publications receiving 6018 citations. Previous affiliations of Xu Liu include Harvard University & Brigham and Women's Hospital.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy.

Kai Mao, +3 more
- 15 Jul 2013 - 
TL;DR: It is reported that mitochondrial fission is important for the progression of mitophagy and this data establish a paradigm for selective organelle degradation.
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Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.

Myungjin Kim, +23 more
- 26 Jan 2016 - 
TL;DR: The identified a homozygous missense mutation, changing a conserved amino acid, in ATG5 in two siblings with congenital ataxia, mental retardation, and developmental delay are identified, demonstrating the critical role of autophagy in preventing neurological diseases and maintaining neuronal health.
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Transcriptional regulation by Pho23 modulates the frequency of autophagosome formation.

Meiyan Jin, +6 more
- 16 Jun 2014 - 
TL;DR: The results identified Pho23 as a master transcriptional repressor for autophagy that regulates the frequency of autophagosome formation through its negative regulation of ATG9.