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Mario Chiariello

Researcher at National Institutes of Health

Publications -  82
Citations -  12096

Mario Chiariello is an academic researcher from National Institutes of Health. The author has contributed to research in topics: G protein-coupled receptor & MAP kinase kinase kinase. The author has an hindex of 33, co-authored 73 publications receiving 10441 citations. Previous affiliations of Mario Chiariello include National Research Council & University of Naples Federico II.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

Omar A. Coso, +7 more
- 30 Jun 1995 - 
TL;DR: It is shown that in COS-7 cells, activated Ras effectively stimulates MAPK but poorly induces JNK activity, which strongly support a critical role for Rac1 and Cdc42 in controlling the JNK signaling pathway.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Role of the small GTPase Rab7 in the late endocytic pathway.

Rosalba Vitelli, +6 more
- 14 Feb 1997 - 
TL;DR: Data indicate that the Rab7 protein in mammalian cells is present on a late endosomal compartment much larger than the compartment labeled by the cation-independent mannose 6-phosphate receptor, which appears to play a fundamental role in controlling late endocytic membrane traffic.
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Activation of the Protein Kinase Akt/PKB by the Formation of E-cadherin-mediated Cell-Cell Junctions EVIDENCE FOR THE ASSOCIATION OF PHOSPHATIDYLINOSITOL 3-KINASE WITH THE E-CADHERIN ADHESION COMPLEX

Salvatore Pece, +3 more
- 02 Jul 1999 - 
TL;DR: Findings indicate that E-cadherins can initiate outside-in signal transducing pathways that regulate the activity of PI 3-kinase and Akt, thus providing a novel molecular mechanism whereby the interaction among neighboring cells and their adhesion status may ultimately control the fate of epithelial cells.