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Journal ArticleDOI

Studies on cellular autophagocytosis. Vinblastine-induced autophagy in the rat liver.

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TLDR
Administration of vinblastine in two doses intraperitoneally to rats induced a prominent formation of autophagic vacuoles in rat liver parenchymal cells, and therefore, offers an excellent model for future studies on autophagy.
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This article is published in Experimental Cell Research.The article was published on 1974-08-01. It has received 139 citations till now. The article focuses on the topics: Vinblastine & Autophagy.

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Citations
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Lysosomal Turnover, but Not a Cellular Level, of Endogenous LC3 is a Marker for Autophagy

TL;DR: The results indicate that endogenous LC3-II is considerably degraded by lysosomal hydrolases after formation of autolysosomes, and suggest that lysOSomal turnover, not a transient amount, of this protein reflects starvation-induced autophagic activity.
References
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Cell Communication, Calcium Ion, and Cyclic Adenosine Monophosphate

TL;DR: The changes in membrane potentials indicate the likelihood of widespread changes in the properties of the cell membrane, for example, changes in Na+ and K+ transport and distribution.
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New hypothesis of insulin secretion.

TL;DR: A working hypothesis is suggested for the events which occur between biochemical stimulation and the liberation of secretory granules into the extracellular space.
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Effect of cyclic AMP on release of lysosomal enzymes from phagocytes.

TL;DR: Phagocytosis of undigestible particles causes the selective extrusion of lysosomal enzymes from macrophages and polymorphonuclear leucocytes and the process can be modified by cyclic nucleotides, prostaglandin E and colchicine.
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Drug-induced erythrocyte membrane internalization

TL;DR: This study provides a basis for proposing a unifying concept of the action of some membrane-active drugs, and for considering the role of erythrocyte membrane internalization in pathophysiologic events.
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